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How common are allergic reactions to foam sclerotherapy?

I have spider veins on my hands and arms and I am interested in foam sclerotherapy treatments. However, I am allergic to a number of different medications and I am worried that I might have an allergic reaction. How common are allergic reactions to these treatments and what are the chemicals or substances that might trigger a reaction?


Doctors Answers (6)

Sclerotherapy is performed with one of the FDA-approved sclerosing agents that are also medical grade detergent. As a detergent, the aqueous solution can be converted to a foam, which increases the potency of the agent primarily by increasing the contact time of the sclerosant with the inside vein lining. Allergies to sclerosants are extremely rare, but if you have a history of general allergic sensitivity I would recommend treating a small number of cosmetic spider veins initially. Then consider limiting the foam use per visit to 5ml of volume and pre-medicate with anti-histamine. We have never seen an allergic reaction to either of these two agents in our practice.

The best answer is on the product literature found on the web site, but generally the answer is very low. This question is best addressed by your health care provider.

Allergic reactions can occur to almost anything in life. You could be allergic to the latex gloves, the solutions used, the compression hose or band aids/tape afterwards. Sotradecol has a sulfur compound in it and seems to have a higher allergic potential. Polidocanol can also have allergic reactions, but seems to be less likely. These are the two solutions that are detergent based compounds used to make foam. I would talk to your physician and discuss your concerns

Allergic reactions to sclerotherapy or foam sclerotherapy are rare to very rare. Most medications that cause allergies are larger more complicated structures than the sclerosants commonly used for foam, but they can occur. On related note i generally dont recommend foam sclerotherapy for spider veins rather liquid sclerotherapy.

The most commonly used sclerothrapy drugs are sodium tetradecyl sulfate and polidocanol. These are available as the FDA-approved drugs, Sotradecol and Asclera, respectively. Allergic reactions to these drugs are extremely rare and usually involve only a rash. Severe, life-threatening reactions have been reported, but they are very rare. There is significant concern that pharmacy-compounded versions of these drugs may not be as safe as the FDA-approved drugs, and I suggest avoiding the compounded drugs.

Allergic reaction is rare with medications used for sclerotherapy.

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