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What causes May Thurner Syndrome?

I just found out that my mother had May Thurner Syndrome. Now I am worried that I may have it too. I am a 33 year old female and fairly active. Is May Thurner Syndrome hereditary? What symptoms should I watch out for?


Doctors Answers (1)

May Thurner Syndrome (iliac vein compression syndrome) is caused by compression of the common venous outflow tract of the left lower extremity under the left common iliac artery. The vein is compressed by the overlaying artery against the lumbar spine causing pain, swelling, and risk of venous thrombosis (DVT) blood clots, in the iliofemoral vein. These variations of anatomy are often not seen by venography. However, intravascular ultrasound (IVUS) has evolved as the best current technique for diagnosis. Functional testing including duplex ultrasound and plethysmography may sometimes be helpful. To rule out other causes for hypercoagulable state, it may be appropriate to check the antithrombin, protein C, protein S, factor V Leiden, and prothrombin G20210A.

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